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NADPH oxidase 2 inhibitors in neuropsychiatric and neurodegenerative diseases

NADPH oxidase 2 inhibitor

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  • ORL1 Receptors

In a dose ranging duration of action PD study, limited brain exposure was observed at the 100 mg/kg dose, and no metabolite (4) could be detected

  • tuskonus
  • December 6, 2022
  • ORL1 Receptors

In clinical trials, subcutaneous burosumab increased serum phosphorus levels in pediatric and adult patients with XLH, as well as significantly improving the severity of rickets in children, and improving pain, stiffness, physical functioning, and fracture/pseudofracture healing in adults

  • tuskonus
  • March 12, 2022
  • ORL1 Receptors

The brain samples were collected for the subsequent immunohistochemistry and western blot experiments

  • tuskonus
  • February 16, 2022
  • ORL1 Receptors

Afterwards, an additional quality check with the Agilent 2100 Bioanalyzer system was performed

  • tuskonus
  • September 10, 2021

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